- Enable Medical founded
- AtriCure established

Three men and a pair of radio frequency energized surgical scissors - AtriCure Bipolar Ablation System clearedFirst-generation Isolator Clamp (LHP1) cleared
- AtriCure Bipolar Ablation System released to market including second-generation Bipolar Ablation Clamp (LHP2) and second-generation Ablation Sensing Unit (ASU2)
- AtriCure received its first CE Mark approval that included the Bipolar Ablation System
- Washington University published the seminal paper on AtriCure’s Bipolar Radiofrequency Technology
- Foundational patent 6,517,536 and 6,546,935 issued for “Device and Methods for Transmural Ablation”
- First commercial sale that included the Bipolar Ablation Clamp
- Lumitip™ Dissector released to market
- First international sale that was sold to Belgium
- Isolator® Transpolar™ Pen (MAX1) released to market
- AtriCure listed on NASDAQ
- AtriCure opened its European office in the Netherlands

AtriCure became publicly traded company on NASDAQ - Isolator® Transpolar™ Long Pen (MAX5) released to market
- Isolator® Transpolar™ System released to market including the Isolator Clamps (OLL1, EMR1 and EML1)
- AtriCure Synergy Bipolar Ablation System released to market including the Isolator® Synergy™ Clamps (OLL2, OSL2, EMR2 and EML2) along with AtriCure Switch Matrix (ABS3)
- First AtriClip® device implanted
- AtriCure entered the Cryosurgical market
- Isolator Coolrail® Linear Pen released to market
- ABLATE Clinical Trial enrollment initiated
- EXCLUDE Clinical Trial enrollment initiated
- Continued to grow international presence by selling products in over 25 countries
- CRYO1 Cryoablation Probe released to market
- ORLab® System released to market
- DEEP (Hybrid) Clinical Trial enrollment initiated
- AtriClip Left Atrial Appendage (LAA) Exclusion System released to marketAtriClip ACH1 device released to market
- CRYO2 cryoICE® Cryoablation probe released to market
- Multifunctional Linear Pen released to market

AtriClip LAA Exclusion System was commercially available in US - AtriCure Cryo Module System released to market
- Isolator Synergy System approved for treatment of persistent or long-standing persistent atrial fibrillation
- Isolator® Synergy Access® clamp released to market
- AtriClip PRO® device released to market
- DEEP (Staged) Clinical Trial enrollment initiated
- Maze IV Training Program initiated
- AtriCure hosted 25th Anniversary of the Cox-Maze Procedure
- Over 100,000 ablations performed
- Established Professional Education Program
- AtriCure expanded the Maze IV Training Program to Europe
- AtriCure acquired Endoscopic Technologies, Inc. (Estech)
- AtriClip® FLEX™ device (ACH2) released to market
- CRYO3 cryoICE® Cryoablation Probe and AtriCure Cryo Module Version 6 (ACM V6) released to market
- ABLATE-PAS Clinical Trial completes enrollment
- DEEP (Pivotal) Clinical Trial enrollment initiated
- Completed requirement to train U.S. surgeons on Synergy Clamp per FDA mandate
- Minneapolis office opened
- Over 150,000 ablations performed
- cryoICE® probe made available for Cryo Nerve Block applications
- CEASE-AF Clinical Trial enrollment initiated
- Dr. James L. Cox American Association for Thoracic Surgery (AATS) Fellowship Training Program established
- Introduced Advanced Ablation weekend training courses
- AtriCure acquired nContact Surgical, LLC.
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2015 by Cincinnati Enquirer
- New headquarters opened in Mason, Ohio, near Cincinnati
- 200,000 ablations performed and 50,000 AtriClip devices sold
- Continued to grow international presence by selling products in over 50 countries

Top 50 workplaces in 2015 - AtriClip PRO2® device released to market
- cryoFORM® probe released to market
- ATLAS Clinical Trial enrollment initiated
- FROST Clinical Trial enrollment initiated
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2016 by Cincinnati Enquirer
- The Society of Thoracic Surgeons (STS) 2017 Clinical Practice Guidelines recommend Afib ablation treatment
- Gained approval for the AtriClip® products and cryoICE® platform in Japan
- AtriClip PRO•V® device released to market
- Introduced Nurse Continuing Education Unit (CEU) Course for Ablation and Left Atrial Appendage Management
- Heart Rhythm Society (HRS) provide Class I recommendation
- Over 250,000 ablations performed and surpassed 100,000 AtriClip devices sold worldwide
- AtriClip® FLEX•V® device released to market
- CONVERGE IDE Clinical Trial completes enrollment
- AtriCure and Baheal Group Establish Partnership and China Distribution Agreement
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2018 by Cincinnati Enquirer
- cryoICE cryoSPHERE® probe released to market
- Received expanded labeling claims for AtriClip devices
- ICE-AFIB Clinical Trial enrollment initiated
- First national Fellows Concomitant Ablation Training Course led by Northwestern Faculty Drs. McCarthy and Cox
- AtriCure acquired SentreHEART, Inc.
- Facility expansions at headquarters and European location
- The Society of Thoracic Surgeons (STS) endorses AtriCure’s Advanced Ablation Courses in the United States
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2019 by Cincinnati Enquirer
- Over 2,500 healthcare professionals trained, more than 350,000 ablations performed, and surpassed 200,000 AtriClip devices sold worldwide
- MO100000 marked the 100,000th production build
- aMAZE Clinical Trial completes enrollment
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2020 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2020 National Standard Setter by Minneapolis Star Tribune
- Received expanded labeling for Cryo Nerve Block Therapy
- EPi-Sense® Guided Coagulation System approved for treatment of long-standing persistent atrial fibrillation
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2021 by Cincinnati Enquirer
- AtriCure surpasses one million devices produced
- Isolator® Synergy™ EnCompass® clamp released to market
- HEAL-IST Clinical Trial enrollment initiated
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2022 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2022 National Standard Setter by Minneapolis Star Tribune
- Amsterdam office earned a Great Place to Work Award Netherlands 2022
- AtriCure wins 2022 National Association of Corporate Directors (NACD) Diversity, Equity, & Inclusion Award
- LeAAPS Clinical Trial enrollment initiated
- EPi-Sense ST™ device released to market
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2023 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2023 National Standard Setter by Minneapolis Star Tribune
- Amsterdam office earned a Great Place to Work Award Netherlands 2023 for the second time in company history
- Mike Carrel named the Top Large Business Leader in the Greater Cincinnati region (as part of Top Workplaces awards)
- Multifunctional Ablation Generator (MAG) released to market
- Over 1 million patients treated and surpassed 500,000 AtriClip devices sold worldwide
- cryoSPHERE®+ probe released to market
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2024 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2024 by Minneapolis Star Tribune
- AtriClip® FLEX-Mini™ device released to market
- cryoSPHERE® MAX probe released to market
- Amsterdam office earned a Great Place to Work Award Netherlands 2024 for the third time in company history. The Great Place to Work Award 2024 was also awarded for Australia and United Kingdom
- EPi-Ease™ device released to market
- AtriCure earned a spot on U.S. News & World Report’s 2025–2026 Best Companies to Work For list, for the first time in company history
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2025 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2025 by Minneapolis Star Tribune
- AtriClip PRO-Mini® device released to market
- LeAAPS Clinical Trial completes enrollment
- cryoXT™ probe released to market
- BoxX-NoAF Clinical Trial enrollment initiated
- Mason Headquarters earned Greater Cincinnati’s Top Workplaces 2026 by Cincinnati Enquirer
- Minnetonka office named Top Workplaces 2026 by Minneapolis Star Tribune
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